Aesthetic Treatments


PRF is spun at a slower speed, which allows the layers of the blood to not separate as distinctly. This slower speed doesn’t harshly disrupt the cells, resulting in more pure cells within the plasma. The centrifuge process allows leukocytes (white blood cells) and mesenchymal stem cells to remain within the platelet layer, creating a higher quality plasma. PRF contains about ten times the platelet concentration that is found within the body. A key component of the PRF that differs from PRP is the fibrin matrix. When PRF is placed over treated tissue, it stimulates a fibrin matrix and induces a slower release of growth factors over time. This gradual release of GF further promotes healing and reduces fine lines and wrinkles. Finally, unlike PRP, PRF does not require added anticoagulation. The fibrin matrix described above is formed naturally during the process, without added heparin or sodium citrate to the test tubes, again facilitating a more pure, higher quality plasma.


PRP is composed of 1/3 platelet “rich” plasma and 2/3 platelet “poor” plasma. A contributing factor to this is the high speed in which the blood is centrifuged. PRP is centrifuged at a much faster rate, causing more disruption to cells leading to a higher volume of platelet “poor” plasma. PRP only contains about 2-5 times the body’s platelet concentrate.


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Skin Insights: The Shino Bay Blog

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